Anti-PDGFR alpha antibody [APA5] - Low endotoxin, Azide free (ab171230)
Key features and details
- Rat monoclonal [APA5] to PDGFR alpha - Low endotoxin, Azide free
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Isotype: IgG2a
Related conjugates and formulations
Overview
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Product name
Anti-PDGFR alpha antibody [APA5] - Low endotoxin, Azide free
See all PDGFR alpha primary antibodies -
Description
Rat monoclonal [APA5] to PDGFR alpha - Low endotoxin, Azide free -
Host species
Rat -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Fusion protein corresponding to Mouse PDGFR alpha (extracellular). Fusion protein containing the extracellular domain of Mouse PDGFR alpha and the Fc portion of Human IgG1 purified from the culture supernatant of transfected COS1 cells
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Positive control
- Mouse NIH 3T3 cell line
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General notes
Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Constituent: PBS -
Carrier free
Yes -
Concentration information loading...
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Purity
Affinity purified -
Clonality
Monoclonal -
Clone number
APA5 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab171230 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
Use 1µg for 105-8 cells.
Final test volume = 100 µL ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use 1µg for 105-8 cells. Final test volume = 100 µL ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Target
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Function
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity. -
Tissue specificity
Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue. -
Involvement in disease
Note=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA). -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 18595 Mouse
- SwissProt: P26618 Mouse
- Unigene: 221403 Mouse
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Alternative names
- Alpha-type platelet-derived growth factor receptor antibody
- CD140 antigen-like family member A antibody
- CD140a antibody
see all
Images
Protocols
Datasheets and documents
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Datasheet download
References (0)
ab171230 has not yet been referenced specifically in any publications.