Anti-PDGF Receptor alpha antibody (ab124392)


  • Product nameAnti-PDGF Receptor alpha antibodySee all PDGF Receptor alpha primary antibodies ...
  • Description
    Rabbit polyclonal to PDGF Receptor alpha
  • Tested applicationsWB, IP, IHC-P more details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Cow, Dog, Pig, Xenopus laevis
  • Immunogen

    Synthetic peptide:C-GKRNRHSSQTSEESAIETG conjugated to KLH, corresponding to amino acids 1035-1053 of Human PDGF Receptor alpha.

  • Positive control
    • Human brain, cerebellum tissue; NIH/3T3 cell line lysate



Our Abpromise guarantee covers the use of ab124392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB 1/250 - 1/500. Detects a band of approximately 150,170 kDa (predicted molecular weight: 122 kDa).
IP Use at an assay dependent dilution. 5-10 µl immunoprecipitates PDGF Receptor alpha from 500 µg of NIH/3T3 RIPA lysate.
IHC-P 1/100.


  • FunctionReceptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity.
  • Tissue specificityExpressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue.
  • Involvement in diseaseNote=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA).
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Target information above from: UniProt accession P16234 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • Alpha-type platelet-derived growth factor receptor antibody
    • CD140 antigen-like family member A antibody
    • CD140a antibody
    • CD140a antigen antibody
    • MGC74795 antibody
    • PDGF alpha chain antibody
    • PDGF-R-alpha antibody
    • PDGFR 2 antibody
    • PDGFR alpha antibody
    • PDGFR2 antibody
    • PDGFRA antibody
    • PDGFRA/BCR fusion antibody
    • PGFRA_HUMAN antibody
    • Platelet derived growth factor receptor 2 antibody
    • Platelet derived growth factor receptor alpha antibody
    • Platelet derived growth factor receptor alpha polypeptide antibody
    • Platelet derived growth factor receptor antibody
    • Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein antibody
    • RHEPDGFRA antibody
    see all

Anti-PDGF Receptor alpha antibody images

  • ab124392, at 1/100 dilution, staining PDGF Receptor alpha in formalin-fixed, paraffin-embedded Human brain cerebellum tissue by Immunohistochemistry.

References for Anti-PDGF Receptor alpha antibody (ab124392)

ab124392 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab124392.
Please use the links above to contact us or submit feedback about this product.