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Read our guarantee »Overview
Product name
PDK3 protein
See all PDK3 products (2) ...
Protein description
Recombinant Human PDK3 (amino acid 9-406) with N-terminal His tag. (UniProt ID = Q15120).
Uniprot accession
Q15120
Protein length
398 amino acids
Expression host
E. coli
Properties
Purity
> 90% Purified via His tag
E.C. Number
2.7.11.2
Form
Liquid
Storage instructions
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Storage buffer
pH: 7.50
Constituents: 0.14% Sodium phosphate, 1.46% Sodium chloride, 30% Glycerol, 0.08% DTT, 0.02% EDTA, 0.05% Triton-X-100
Concentration
Concentration information loading...
Research areas
Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Energy transfer pathways >> Energy Metabolism
Metabolism >> Pathways and Processes >> Mitochondrial Metabolism >> Mitochondrial markers
Signal Transduction >> Metabolism >> Mitochondrial
Signal Transduction >> Metabolism >> Energy Metabolism
Applications
Show applications key
Our Abpromise guarantee covers the use of ab110355 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
FuncS: Use at an assay dependent concentration. See MitoSciences activity protocol.
sELISA: Use at an assay dependent dilution.
Application notes
This peptide can be used with studies using ab110671.
Protein info
Function
Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Tissue specificity
Found almost exclusively in heart and skeletal muscle.
Sequence similarities
Belongs to the PDK/BCKDK protein kinase family.
Contains 1 histidine kinase domain.
Cellular localization
Mitochondrion matrix.
Target information above from: UniProt accessionQ15120
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Protocols
References for PDK3 protein (ab110355)
ab110355 has not yet been referenced specifically in any publications.
Publishing research using ab110355? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"