Anti-PDSS2 antibody (ab96324)

Overview

• Product nameAnti-PDSS2 antibodySee all PDSS2 primary antibodies ...
• Description
  Rabbit polyclonal to PDSS2
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat, Cow, Pig
• Immunogen

  Recombinant fragment, corresponding to a region within amino acids 88-321 of Human PDSS2 (NP_065114).

• Positive controlA431 whole cell lysate

Properties

• FormLiquid
• Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
  Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Cancer
  • Oncoproteins/suppressors
  • Tumor suppressors
  • Other

  • Signal Transduction
  • Metabolism
  • Energy Metabolism

  • Signal Transduction
  • Metabolism
  • Mitochondrial

Applications

Target

• FunctionSupplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.
• PathwayCofactor biosynthesis; ubiquinone biosynthesis.
• Involvement in diseaseDefects in PDSS2 are a cause of coenzyme Q10 deficiency (COQ10D) [MIM:607426]. Coenzyme Q10 deficiency is an autosomal recessive disorder with variable manifestations. It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy.
• Sequence similaritiesBelongs to the FPP/GGPP synthase family.
• Cellular localizationMitochondrion.

Target information above from: UniProt accession Q86YH6 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 521115 Cow
  • Entrez Gene: 57107 Human
  • Entrez Gene: 57107 Human
  • Entrez Gene: 71365 Mouse
  • Entrez Gene: 100312977 Pig
  • Entrez Gene: 365592 Rat
  • Omim: 610564 Human
  • SwissProt: Q86YH6 Human

  • SwissProt: Q86YH6 Human
  • SwissProt: Q33DR3 Mouse
  • SwissProt: Q5U2R1 Rat
  • Unigene: 486095 Human
  • Unigene: 363225 Mouse
  • Unigene: 20063 Rat

  see all

• Alternative names
  All-trans-decaprenyl-diphosphate synthase subunit 2 antibodybA59I9.3 antibodyC6orf210 antibody

  Candidate tumor suppressor protein antibodychromosome 6 open reading frame 210 antibodyDecaprenyl pyrophosphate synthase subunit 2 antibodydecaprenyl pyrophosphate synthetase subunit 2 antibodyDecaprenyl-diphosphate synthase subunit 2 antibodyDLP1 antibodyDLP1_HUMAN antibodyhDLP1 antibodyPdss2 antibodyprenyl (decaprenyl) diphosphate synthase, subunit 2 antibodysubunit 2 of decaprenyl diphosphate synthase antibody

  see all

Anti-PDSS2 antibody images

• 

  Western blot - PDSS2 antibody (ab96324)
  Anti-PDSS2 antibody (ab96324) at 1/1000 dilution + A431 whole cell lysate at 30 µg
  
  Predicted band size : 44 kDa