Anti-PFKFB1 antibody - N-terminal (ab71626)

Overview

• Product nameAnti-PFKFB1 antibody - N-terminalSee all PFKFB1 primary antibodies ...
• Description
  Rabbit polyclonal to PFKFB1 - N-terminal
• Tested applicationsELISA, WB, IHC-P more details
• Species reactivity
  Reacts with: Mouse, Human
  
• Immunogen

  Synthetic peptide from the N terminal region of human PFKFB1 conjugated to KLH

• Positive control
  • Jurkat cell line lysate and human hepatocarcinoma tissue.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• PurityProtein G purified
• Purification notesab71626 is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Metabolism
  • Energy Metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Metabolism
  • Types of disease
  • Cancer

Applications

Target

• FunctionSynthesis and degradation of fructose 2,6-bisphosphate.
• Tissue specificityLiver.
• Sequence similaritiesIn the C-terminal section; belongs to the phosphoglycerate mutase family.

• Target information above from: UniProt accession P16118 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 5207 Human
  • Entrez Gene: 5208 Human
  • Entrez Gene: 5209 Human
  • Entrez Gene: 5210 Human
  • Entrez Gene: 18639 Mouse
  • Entrez Gene: 18640 Mouse
  • Entrez Gene: 270198 Mouse
  • Omim: 311790 Human

  • SwissProt: O60825 Human
  • SwissProt: P16118 Human
  • SwissProt: Q16875 Human
  • SwissProt: Q16877 Human
  • SwissProt: P70265 Mouse
  • SwissProt: P70266 Mouse
  • SwissProt: Q6DTY7 Mouse
  • Unigene: 195471 Human
  • Unigene: 282702 Human
  • Unigene: 444304 Human
  • Unigene: 476217 Human
  • Unigene: 132391 Mouse
  • Unigene: 249131 Mouse
  • Unigene: 249861 Mouse

  see all
• Alternative names
  • 6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 1 antibody
  • 6-bisphosphatase antibody
  • 6-P2ase 1 antibody

  • 6-P2ASE liver isozyme antibody
  • 6PF 2 K/Fru 2 6 P2ASE liver isozyme antibody
  • 6PF 2 K/Fru 2,6 P2ase 1 antibody
  • 6PF-2-K/Fru-2 antibody
  • F261_HUMAN antibody
  • F6PK antibody
  • Fructose 2 6 bisphosphatase antibody
  • Fructose 6 phosphate 2 kinase:fructose 2 6 bisphosphatase antibody
  • Fructose-2 antibody
  • HL2K antibody
  • MGC116715 antibody
  • MGC116717 antibody
  • PFK/FBPase 1 antibody
  • PFKFB 1 antibody
  • Pfkfb1 antibody
  • PFRX antibody

  see all

Anti-PFKFB1 antibody - N-terminal images

• 

  Western blot - PFKFB1 antibody - N-terminal (ab71626)
  Anti-PFKFB1 antibody - N-terminal (ab71626) at 1/240 dilution + Jurkat cell line lysate at 35 µg
  
  Predicted band size : 55 kDa
  Observed band size : 60 kDa (why is the actual band size different from the predicted?)
  
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PFKFB1 antibody - N-terminal (ab71626)
  ab71626 at 1/50 dilution, staining PFKFB1 in human hepatocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.