![Western blot - PGRP1B antibody [186C426] (ab13681) image](#abcam1-13681.gif)
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Product name
Anti-PGRP1B antibody [186C426]
Description
Mouse monoclonal [186C426] to PGRP1B
Tested applications
Cross reactivity
Predicted to work with
Mouse, Rat, Human, Pig
Immunogen
Synthetic peptide: CSQRLRELQAHHVHNN conjugated to KLH, corresponding to amino acids 95-110 of Human PGRP1B.
CSQRLRELQAHHVHNN
Positive control
Whole cell lysate from human brain.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
186C426
Isotype
IgG1
Research areas
Microbiology >> Protein >> Human Protein >> Defensin
Immunology >> Innate Immunity >> Macrophage / Inflamm.
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Western blot - PGRP1B antibody [186C426] (ab13681)
![Western blot - PGRP1B antibody [186C426] (ab13681) image](/ps/datasheet/Images/13/ab13681/abcam1-13681.gif)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab13681 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 2 µg/ml. Predicted molecular weight: 44.2 kDa.
Target
Function
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Tissue specificity
Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus.
Sequence similarities
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
Post-translational
modifications
N-glycosylated.
Cellular localization
Secreted.
Target information above from: UniProt accessionQ96LB8
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Peptidoglycan recognition protein 4 antibody
- Peptidoglycan recognition protein I-beta antibody
- Peptidoglycan recognition protein intermediate beta antibody
see all
Database links
- Entrez Gene: 57115 Human
- Entrez Gene: 384997 Mouse
- Entrez Gene: 310611 Rat
- Omim: 608198 Human
- SwissProt: Q96LB8 Human
- SwissProt: Q0VB07 Mouse
- Unigene: 58356 Human
- Unigene: 316644 Mouse
Anti-PGRP1B antibody [186C426] images:
Western blot - PGRP1B antibody [186C426] (ab13681)
Predicted band size : 44.2 kDa
Western blot analysis of PGRP1B in cell lysates from human brain using ab13681 at a dilution of 2 µg/ml.
References for Anti-PGRP1B antibody [186C426] (ab13681)
ab13681 has not yet been referenced specifically in any publications.
Publishing research using ab13681? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"