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Read our guarantee »Products:Signal Transduction >> Protein Trafficking >> Organelle Proteins
Anti-PHYH antibody
See all PHYH products (3) ...
Mouse monoclonal to PHYH
Reacts with
Human
Recombinant full length protein, corresponding to amino acids 1-339 of Human PHYH
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: None
PBS, pH 7.2
Concentration information loading...
Protein G purified
Monoclonal
IgG1
kappa
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Signal Transduction >> Metabolism >> Lipid metabolism
Signal Transduction >> Metabolism >> Vitamins / Minerals
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Sensory System >> Auditory system
Neuroscience >> Sensory System >> Visual system
Signal Transduction >> Protein Trafficking >> Organelle Proteins
Western blot - PHYH antibody (ab55585)
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Our Abpromise guarantee covers the use of ab55585 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
Expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle.
Lipid metabolism; fatty acid metabolism.
Defects in PHYH are a cause of Refsum disease (RD) [MIM:266500]. RD is an autosomal recessive disorder characterized clinically by a tetrad of abnormalities: retinitis pigmentosa, peripheral neuropathy, cerebellar ataxia, and elevated protein levels in the cerebrospinal fluid (CSF). Patients exhibit accumulation of the branched-chain fatty acid, phytanic acid, in blood and tissues. Less constant features are nerve deafness, anosmia, skeletal abnormalities, ichthyosis, cataracts and cardiac impairment. Manifestations of the disease appear in the second or third decade of life.
Belongs to the PhyH family.
Peroxisome.
Target information above from: UniProt accessionO14832
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Western blot - PHYH antibody (ab55585)

Western blot against tagged recombinant protein immunogen using ab55585 PHYH antibody at 1ug/ml. Predicted band size of immunogen is 63 kDa
ab55585 has not yet been referenced specifically in any publications.
Publishing research using ab55585? Please let us know so that we can cite the reference in this datasheet
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