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Anti-PI 3 Kinase catalytic subunit gamma antibody (ab3537)

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Overview

Product name

Anti-PI 3 Kinase catalytic subunit gamma antibody
See all PI 3 Kinase catalytic subunit gamma products (5) ...

Description

Goat polyclonal to PI 3 Kinase catalytic subunit gamma

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat

Immunogen

Synthetic peptide: VLGIKQGEKHSA, corresponding to C terminal amino acids 1091-1102 of Human PIK3CG.

C-VLGIKQGEKHSA

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

Human Heart lysate.

General notes

Principal Names – PIK3CG; PI3K; PIK3; PI3CG; PI3Kgamma; phosphoinositide-3-kinase, catalytic, gamma polypeptide; PI3-kinase; p110-gamma; PTDINS-3-kinase; 1-phosphatidylinositol 3-kinase; phosphatidylinositol 3 kinase gamma, p110 gamma; phosphoinositide-3-kinase gamma catalytic subunit; phosphatidylinositol 3-kinase catalytic 110-kD gamma; phosphatidylinositol 3-kinase, catalytic, gamma polypeptide. Official Gene Symbol - PIK3CG. GenBank Accession Number – NP_002640. LocusLink ID - 5294 (human); 30955 (mouse). Gene Ontology terms - 1-phosphatidylinositol 3-kinase; G-protein coupled receptor protein signaling pathway.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 5mg/ml Tris, pH 7.3

Concentration

Concentration information loading...

Purity

IgG fraction

Purification notes

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Clonality

Polyclonal

Isotype

IgG

Research areas

Immunology >> Innate Immunity >> TLR Signaling
Cancer >> Signal transduction >> G protein signaling >> GPCR
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR
Signal Transduction >> Signaling Pathway >> Lipid Signaling >> Lipid Kinases

  • Western blot - PI 3 Kinase catalytic subunit gamma antibody (ab3537)Western blot - PI 3 Kinase catalytic subunit gamma antibody (ab3537) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab3537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 110-120 kDa (predicted molecular weight: 121 kDa).

Target

Function

3-phosphorylates the cellular phosphoinositide PtdIns-4,5-biphosphate (PtdIns(4,5)P2) to produce PtdIns-3, 4,5-triiphosphate (PtdIns(3,4,5)P3). Links G-protein coupled receptor activation to the secondary messenger PtdIns(3,4,5)P3 production.

Tissue specificity

Pancreas, skeletal muscle, liver and heart.

Pathway

Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.

Sequence similarities

Belongs to the PI3/PI4-kinase family.
Contains 1 PI3K/PI4K domain.

Target information above from: UniProt accessionP48736 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • 1 phosphatidylinositol 3 kinase antibody
  • 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma antibody
  • 5-bisphosphate 3-kinase catalytic subunit gamma isoform antibody
  • p110 gamma antibody
  • p110gamma antibody
  • p120 PI3K antibody
  • p120-PI3K antibody
  • Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit gamma isoform antibody
  • Phosphatidylinositol-4 antibody
  • Phosphoinositide 3 kinase catalytic gamma polypeptide antibody
  • PI3 kinase p110 subunit gamma antibody
  • PI3-kinase subunit gamma antibody
  • PI3CG antibody
  • PI3K antibody
  • PI3K-gamma antibody
  • PI3Kgamma antibody
  • PIK3 antibody
  • Pik3cg antibody
  • PK3CG_HUMAN antibody
  • PtdIns-3-kinase subunit gamma antibody
  • PtdIns-3-kinase subunit p110-gamma antibody
  • Serine/threonine protein kinase PIK3CG antibody
see all

Database links

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Anti-PI 3 Kinase catalytic subunit gamma antibody images:

  Western blot - PI 3 Kinase catalytic subunit gamma antibody (ab3537)

Western blot - PI 3 Kinase catalytic subunit gamma antibody (ab3537)



Predicted band size : 121 kDa


ab3537 staining (2µg/ml) of Human Heart lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

References for Anti-PI 3 Kinase catalytic subunit gamma antibody (ab3537)

ab3537 has not yet been referenced specifically in any publications.

Publishing research using ab3537? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"