Anti-PI3 Kinase p110 beta antibody (ab55593)

Overview

• Product nameAnti-PI3 Kinase p110 beta antibodySee all PI3 Kinase p110 beta primary antibodies ...
• Description
  Mouse monoclonal to PI3 Kinase p110 beta
• Tested applicationsIHC-P, WB, Flow Cyt more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant fragment, corresponding to amino acids 147-257 of Human PI3 Kinase p110 beta

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  PBS, pH 7.2
• Concentration information loading...
• PurityProtein G purified
• Clonality Monoclonal
• IsotypeIgG2a
• Light chain typekappa
• Research Areas
  • Signal Transduction
  • Signaling Pathway
  • Lipid Signaling
  • Lipid Kinases

  • Immunology
  • Innate Immunity
  • TLR Signaling

  • Cell Biology
  • Cell Cycle
  • Kinases/Phosphatases
  • Other

Applications

Target

• FunctionPhosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.
• Tissue specificityExpressed ubiquitously.
• PathwayPhospholipid metabolism; phosphatidylinositol phosphate biosynthesis.
• Sequence similaritiesBelongs to the PI3/PI4-kinase family.
  Contains 1 PI3K/PI4K domain.

Target information above from: UniProt accession P42338 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 5291 Human
  • Entrez Gene: 5291 Human
  • Omim: 602925 Human
  • SwissProt: Q24JU2 Human
  • SwissProt: P42338 Human
  • SwissProt: P42338 Human
  • Unigene: 239818 Human

• Alternative names
  5-bisphosphate 3-kinase 110 kDa catalytic subunit beta antibody5-bisphosphate 3-kinase catalytic subunit beta isoform antibodyDKFZp779K1237 antibody

  MGC133043 antibodyOTTHUMP00000216901 antibodyOTTHUMP00000216904 antibodyp110 BETA antibodyp110Beta antibodyPhosphatidylinositol 3 kinase catalytic beta polypeptide antibodyPhosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit beta antibodyPhosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit beta isoform antibodyPhosphatidylinositol-4 antibodyPhosphoinositide 3 kinase catalytic beta polypeptide antibodyPI3 kinase p110 subunit beta antibodyPI3-kinase subunit beta antibodyPI3K antibodyPI3K beta antibodyPI3K-beta antibodyPI3Kbeta antibodyPI3KCB antibodyPIK3C1 antibodyPik3cb antibodyPK3CB_HUMAN antibodyPtdIns 3 kinase p110 antibodyPtdIns-3-kinase subunit beta antibodyPtdIns-3-kinase subunit p110-beta antibody

  see all

Anti-PI3 Kinase p110 beta antibody images

• 

  IHC-P - PI3 Kinase p110 beta antibody (ab55593)
  PI3 Kinase p110 beta antibody (ab55593) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lymph node.
• 

  Western blot - PI3 Kinase p110 beta antibody (ab55593)
  Western blot against tagged recombinant protein immunogen using ab55593 PI3 Kinase p110 beta antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa
• 

  Flow Cytometry-Anti-PI3 Kinase p110 beta antibody(ab55593)
  Overlay histogram showing Jurkat cells stained with ab55593 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab55593, 1µg/1x10⁶ cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1µg/1x10⁶ cells) used under the same conditions. Acquisition of >5,000 events was performed.