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Read our guarantee »Products:Neuroscience >> Neurotransmission >> Secretory Vesicles >> Regulation
Anti-PICK1 antibody
See all PICK1 products (7) ...
Mouse monoclonal to PICK1
Reacts with
Human
Recombinant fragment, corresponding to amino acids 266-376 of Human PICK1
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: None
PBS, pH 7.2
Concentration information loading...
Protein G purified
Monoclonal
IgG2a
kappa
Signal Transduction >> Protein Trafficking >> Vesicle Transport >> Regulation
Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Receptor Tyrosine Kinases
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> PKC
Neuroscience >> Neurotransmission >> Secretory Vesicles >> Regulation
Western blot - PICK1 antibody (ab56586)
(enlarge)
Our Abpromise guarantee covers the use of ab56586 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ACCN3/ACCN2 channel.
Ubiquitous.
Contains 1 AH domain.
Contains 1 PDZ (DHR) domain.
Phosphorylation at Thr-82 appears to inhibit the interaction with AMPA receptors.
Cytoplasm > perinuclear region. Cell junction > synapse. Also present at excitatory synapses.
Target information above from: UniProt accessionQ9NRD5
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Western blot - PICK1 antibody (ab56586)

Western blot against tagged recombinant protein immunogen using ab56586 PICK1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa
ab56586 has not yet been referenced specifically in any publications.
Publishing research using ab56586? Please let us know so that we can cite the reference in this datasheet
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Concentration not available for this lot.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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