Anti-PKC mu antibody (ab59366)

Overview

• Product nameAnti-PKC mu antibodySee all PKC mu primary antibodies ...
• Description
  Rabbit polyclonal to PKC mu
• Specificityab59366 detects endogenous levels of total PKC mu protein
• Tested applicationsELISA, IHC-P more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse
• Immunogen

  Synthesized non-phosphopeptide derived from human PKC mu around the phosphorylation site of serine 205 (R-L-S^P-N-V).

• Positive controlHuman brain tissue

Properties

• FormLiquid
• Storage instructionsStore at -20°C. Stable for 12 months at -20°C
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesAffinity-purified from rabbit antiserum by affinity-chromatography, using epitope-specific immunogen
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipid metabolism

  • Metabolism
  • Types of disease
  • Cancer

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of lipids and lipoproteins

  • Signal Transduction
  • Protein Phosphorylation
  • Ser / Thr Kinases
  • PKC

Applications

Target

• FunctionConverts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.
• Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
  Contains 1 PH domain.
  Contains 2 phorbol-ester/DAG-type zinc fingers.
  Contains 1 protein kinase domain.
• Cellular localizationCytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.

Target information above from: UniProt accession Q15139 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 5587 Human
  • Entrez Gene: 18760 Mouse
  • Omim: 605435 Human
  • SwissProt: Q15139 Human
  • SwissProt: Q62101 Mouse
  • Unigene: 508999 Human
  • Unigene: 133719 Mouse

• Alternative names
  KPCD1_HUMAN antibodynPKC D1 antibodynPKC mu antibody

  nPKC-D1 antibodynPKC-mu antibodynPKCD1 antibodynPKCmu antibodyPKC antibodyPKC MU antibodyPKCM antibodyPKCmu antibodyPKD 1 antibodyPKD antibodyPKD1 antibodyPRKCM antibodyPRKD 1 antibodyPRKD1 antibodyProtein kinase C mu antibodyProtein kinase C mu type antibodyProtein kinase D antibodyProtein kinase D1 antibodySerine/threonine protein kinase D1 antibodySerine/threonine-protein kinase D1 antibody

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Anti-PKC mu antibody images

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PKC mu antibody (ab59366)
  ab59366, at a 1/50 dilution, staining human PKC mu in brain, using Immunohistochemistry, Formalin/PFA fixed Paraffin embedded tissue, minus immunising peptide (left image) and plus immunising peptide (right image).