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PP2

Product code: ab120308 (formerly Asc-308)

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Overview

Product name

PP2

Description

Src and RIP2 kinase inhibitor

Biological description

Inhibitor of the Src family of kinases. Inhibits Src and Lck kinase (IC50 values of 36 nM and 31 nM respectively). Also shown to inhibit RIP2, and CK1d (IC50 values are 19 nM and 41 nM respectively).

Purity

> 98%

General notes

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Properties

Chemical name

1-tert-Butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Molecular Weight

301.78

Chemical structure

Chemical Structure

Molecular formula

C15H16ClN5

CAS Number

172889-27-9

Solubility

Soluble in DMSO to 25 mM and in ethanol to 10 mM

Storage instructions

Store at +4°C (desiccating conditions). Do not freeze.

Research areas

Biochemicals >> Pharmacology >> Enzymes >> Kinase >> Src >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals

References for PP2 (ab120308)

This product has been referenced in:

See all 2 publications for this product

Publishing research using ab120308? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"