PPAR alpha peptide (ab4998)
- Product namePPAR alpha peptideSee all PPAR alpha proteins and peptides ...
Our Abpromise guarantee covers the use of ab4998 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Additional Notes
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and mouse phospho-PPAR alpha (Ser12), catalog ab3484. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (70-fold) for competitive inhibition of antibody-protein binding reactions.
- Concentration information loading...
Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Nuclear receptor subfamily 1 group C member 1
- Peroxisome Proliferator Activated Receptor alpha
- Peroxisome proliferator-activated receptor alpha
- FunctionLigand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
- Tissue specificitySkeletal muscle, liver, heart and kidney.
- Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
- Cellular localizationNucleus.
References for PPAR alpha peptide (ab4998)
ab4998 has not yet been referenced specifically in any publications.