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Product Name
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PR3 antibody [1B10]
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See all PR3 antibodies (10)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [1B10] to PR3
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Immunogen
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Human proteinase PR3 purified leukocyte mass.
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Reacts with
(species key)
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Hu
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Specificity
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ab10197, 10198, 10199, 10200 and 10201 detect different determinants of proteinase PR3 which have not been fully determined.
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Tested applications
(see key)
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ELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions ELISA: Use at an assay dependent dilution.
Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> Other Enzymes Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Proteins >> Collagen Signal Transduction >> Cytoskeleton / ECM >> Basal Lamina
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Relevance
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Myeloblastin (PR3) is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. PR3 plays a role in neutrophil response to inflammation.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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1B10
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Myeloma
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Sp2/0
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Isotype
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IgG2a
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.1% Sodium Azide Constituents: PBS, pH 7.4 Material safety datasheet (MSDS) for this product: Sodium Azide MSDS
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Purification notes
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Purified by chromatography on protein A sepharose. Purity is tested by electrophoresis.
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Form
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Liquid
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Concentration
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2.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Notes
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Concentration varies from lot to lot and can be provided on request.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PR3 antibody [1B10] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to PR3
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PR3 antibody [1B10] - more information
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Customer reviews (feedback) regarding PR3 antibody [1B10] |
Customer FAQs regarding PR3 antibody [1B10] |
Protocols for PR3 antibody [1B10] |
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PR3 antibody [1B10] - related products:
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PR3 antibody [1B10] - other tools:
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Contact Abcam with a Technical Enquiry about PR3 antibody [1B10] |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"