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Product Name 

PR3 antibody [1B10]

 

See all PR3 antibodies (10)...

Product type 

Primary antibodies

Description 

Mouse monoclonal [1B10] to PR3

Immunogen 

Human proteinase PR3 purified leukocyte mass.

Reacts with 
(species key)

Hu

Specificity 

ab10197, 10198, 10199, 10200 and 10201 detect different determinants of proteinase PR3 which have not been fully determined.

Tested applications 
(see key)

ELISA


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> Other Enzymes
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Proteins >> Collagen
Signal Transduction >> Cytoskeleton / ECM >> Basal Lamina

Relevance 

Myeloblastin (PR3) is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. PR3 plays a role in neutrophil response to inflammation.

 

Alternative names PR3 antibody [1B10] (ab10197)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

5657    (Human)

Omim

    

177020    (Human)

SwissProt

    

P24158    (Human)

Unigene

    

928    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

1B10

Myeloma 

Sp2/0

Isotype 

IgG2a

Purity 

Protein A purified

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Purified by chromatography on protein A sepharose. Purity is tested by electrophoresis.

Form 

Liquid

Concentration 

2.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes 

Concentration varies from lot to lot and can be provided on request.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PR3 antibody [1B10] is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to PR3

 

PR3 antibody [1B10] - more information

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PR3 antibody [1B10] - other tools:

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