PRG2 antibody [BMK-13] (ab48372)

Product Name 

PRG2 antibody [BMK-13]

Product type 

Primary antibodies

Description 

Mouse monoclonal [BMK-13] to PRG2

Immunogen 

The details of the immunogen for this antibody are not available.

Reacts with 
(species key)

Hu

Specificity 

This antibody is specific for PRG2 protein.

Tested applications 
(see key)

ELISA, IHC-Fr, IHC-P

Abreviews 

Customer reviews (see key)

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Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
IHC-P: Use at an assay dependent dilution.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Secreted. Note=The proform is secreted. The mature protein is found in the matrix of the eosinophil's large specific granule (crystalloid core).

Research areas 

Tags & Cell Markers >> Cell Type Markers >> Other Cell Types
Immunology >> Cell Type Markers >> CD >> NK Cells
Immunology >> Adaptive Immunity >> T Cells >> Cytotoxic Cells

Relevance 

PRG2 is a cytotoxin and helminthotoxin. It also induces noncytolytic histamine release from human basophils and is involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. In pregnancy serum, the proform exists as a disulfide-linked 2:2 heterotetramer with PAPPA, as a disulfide-linked 2:2 heterotetramer with AGT, and as a complex (probably a 2:2:2 heterohexamer) with AGT and C3dg.

Database links 

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

BMK-13

Isotype 

IgG1

Purity 

Tissue culture supernatant

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: Tissue culture supernatant

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

Batch dependent within range: 0.01 - 0.01 mg/ml

Concentration of lot no.     is  

Concentration not available for this lot.

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Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

References for PRG2 antibody [BMK-13] (ab48372)

  This product has been used in:

Leung SY et al. Resolution of allergic airways inflammation but persistence of airway smooth muscle proliferation after repeated allergen exposures. Clin Exp Allergy 34:213-20 (2004). PubMed: 14987300

If you publish research using ab48372 please let us know so that we can cite the reference on this datasheet.

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