Anti-PRX-1 antibody (ab106834)
Key features and details
- Goat polyclonal to PRX-1
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
-
Product name
Anti-PRX-1 antibody
See all PRX-1 primary antibodies -
Description
Goat polyclonal to PRX-1 -
Host species
Goat -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat, Chicken, Cow, Dog -
Immunogen
Synthetic peptide corresponding to Human PRX-1 aa 73-83 (N terminal).
Sequence:C-GSDTPQQDNDQ,
-
Positive control
- LNCaP and mouse heart cell lysates
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106834 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 27 kDa).
1 hour primary incubation is recommended for this product. |
Notes |
---|
WB
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 27 kDa). 1 hour primary incubation is recommended for this product. |
Target
-
Function
Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer. -
Sequence similarities
Belongs to the paired homeobox family.
Contains 1 homeobox DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
-
Database links
- Entrez Gene: 373941 Chicken
- Entrez Gene: 540901 Cow
- Entrez Gene: 609105 Dog
- Entrez Gene: 5396 Human
- Entrez Gene: 18933 Mouse
- Entrez Gene: 266813 Rat
- Omim: 167420 Human
- SwissProt: Q05437 Chicken
see all -
Form
There are 2 isoforms produced by alternative splicing. -
Alternative names
- AGOTC antibody
- Homeobox protein PHOX1 antibody
- Paired mesoderm homeo box 1 antibody
see all
Images
Datasheets and documents
-
Datasheet download
References (2)
ab106834 has been referenced in 2 publications.
- Huang X et al. PRRX1/FOXM1 reduces gemcitabin-induced cytotoxicity by regulating autophagy in bladder cancer. Transl Androl Urol 11:1116-1129 (2022). PubMed: 36092834
- Gong X et al. Effect of heme oxygenase 1 and renin/prorenin receptor on oxidized low-density lipoprotein-induced human umbilical vein endothelial cells. Exp Ther Med 18:1752-1760 (2019). PubMed: 31410134