Overview

  • Product name
    Anti-PTGIS antibody - N-terminal
    See all PTGIS primary antibodies
  • Description
    Rabbit polyclonal to PTGIS - N-terminal
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide (Human) conjugated to KLH from the N-terminus

  • Positive control
    • Mouse lung tissue lysate

Applications

Our Abpromise guarantee covers the use of ab79846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa).

Target

  • Function
    Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
  • Tissue specificity
    Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate.
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CYP8 antibody
    • CYP8A1 antibody
    • Cytochrome P450, family 8, subfamily A, polypeptide 1 antibody
    • EC 5.3.99.4 antibody
    • MGC126858 antibody
    • MGC126860 antibody
    • OTTHUMP00000031777 antibody
    • PGIS antibody
    • Prostacyclin synthase antibody
    • Prostaglandin I2 (prostacyclin) synthase antibody
    • Prostaglandin I2 synthase antibody
    • PTGI antibody
    • PTGIS antibody
    • PTGIS_HUMAN antibody
    see all

Images

  • Anti-PTGIS antibody - N-terminal (ab79846) at 1/50 dilution + Mouse lung tissue lysate at 35 µg

    Predicted band size : 57 kDa
    Observed band size : 57 kDa

References

This product has been referenced in:
  • Chabbi-Achengli Y  et al. Serotonin 2B Receptor (5-HT2B R) Signals through Prostacyclin and PPAR-ß/d in Osteoblasts. PLoS One 8:e75783 (2013). WB ; Human . Read more (PubMed: 24069449) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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