Anti-PTGIS antibody (ab72952)

Overview

• Product nameAnti-PTGIS antibodySee all PTGIS primary antibodies ...
• Description
  Mouse polyclonal to PTGIS
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Full length human PTGIS protein (NP_000952.1)

• Positive controlPTGIS transfected 293T cell line

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS, pH 7.2
• Concentration information loading...
• PurityProtein A purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Cytochromes

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipases

  • Metabolism
  • Pathways and Processes
  • Endocrine metabolism
  • Hormone biosynthesis

  • Developmental Biology
  • Reproduction
  • Placental development

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Hormone biosynthesis

  • Signal Transduction
  • Signaling Pathway
  • Lipid Signaling
  • Prostaglandins

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipid Metabolism
  • Cytochromes

Applications

Target

• FunctionCatalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
• Tissue specificityWidely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate.
• Sequence similaritiesBelongs to the cytochrome P450 family.
• Cellular localizationEndoplasmic reticulum membrane.

Target information above from: UniProt accession Q16647 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 5740 Human
  • Omim: 601699 Human
  • SwissProt: Q16647 Human
  • Unigene: 302085 Human

• Alternative names
  CYP8 antibodyCYP8A1 antibodyCytochrome P450, family 8, subfamily A, polypeptide 1 antibody

  EC 5.3.99.4 antibodyMGC126858 antibodyMGC126860 antibodyOTTHUMP00000031777 antibodyPGIS antibodyProstacyclin synthase antibodyProstaglandin I2 (prostacyclin) synthase antibodyProstaglandin I2 synthase antibodyPTGI antibodyPTGIS antibodyPTGIS_HUMAN antibody

  see all

Anti-PTGIS antibody images

• 

  Western blot - PTGIS antibody (ab72952)
  All lanes : Anti-PTGIS antibody (ab72952) at 1/500 dilution
  
  Lane 1 : PTGIS transfected 293T cell line
  Lane 2 : non transfected 293T cell line
  
  Lysates/proteins at 25 µg per lane.
  
  Secondary
  Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
  
  Predicted band size : 57 kDa
  Observed band size : 50 kDa (why is the actual band size different from the predicted?)