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Product Name
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PTP mu antibody [SK15]
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See all PTP mu antibodies (4)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [SK15] to PTP mu
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Immunogen
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Human PTP mu.
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Reacts with
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Hu
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Does not react with
(species key)
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Ms, Rat
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Specificity
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ab30321 recognises Tyrosine Phosphatase Mu.
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Tested applications
(see key)
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IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IP: Use at a concentration of 1.0 µg/sample.
WB: Use at a concentration of 2.5 µg/ml. Predicted molecular weight: 162 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Type 1 membrane protein
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Research areas
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Signal Transduction >> Protein Phosphorylation >> Tyrosine Phosphatases
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Relevance
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PTP mu is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion.
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PTP mu antibody [SK15] (ab30321) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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SK15
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Myeloma
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Sp2/0
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Isotype
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IgG1
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.01% Sodium Azide
Constituents: 50% Glycerol, 1.0mg/ml BSA Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
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Purification notes
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IgG is protein A purified and dialyzed against PBS.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this PTP mu antibody [SK15] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to PTP mu
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PTP mu antibody [SK15] - more information
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