You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-PTP4A3 antibody (ab26947)

CodeSizePriceAbpointsAvailability
    
Add to basket
 

  • -

  •   
  •   
  •   

  •  

  •  
  •  

  •  

  •  
Updating...

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »

Overview

Product name

Anti-PTP4A3 antibody
See all PTP4A3 products (5) ...

Description

Rabbit polyclonal to PTP4A3

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant full length protein (Human)

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: Whole serum

Purity

Whole antiserum

Clonality

Polyclonal

Isotype

IgG

Research areas

Cardiovascular >> Heart >> Hypertrophy >> Other
Signal Transduction >> Protein Phosphorylation >> Tyrosine Phosphatases
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated

  • Western blot - PTP4A3 antibody (ab26947)Western blot - PTP4A3 antibody (ab26947) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab26947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: 1/5000. Predicted mo...Read more →

    WB: 1/5000. Predicted molecular weight: 19 kDa.

  • ELISA

     ELISA: 1/100000.

    ELISA: 1/100000.

Target

Relevance

PTP4A3 protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. It enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. It may be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. PTP4A3 interacts with tubulin. It belongs to the protein tyrosine phosphatase family. It is mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. It is consistently overexpressed in colon cancer metastasis.

Cellular localization

Plasma membrane and early endosome.

Alternative names

  • Potentially prenylated protein tyrosine phosphatase antibody
  • PRL3 antibody
  • PRLR antibody
  • Protein tyrosine phosphatase 4a3 antibody
  • Protein tyrosine phosphatase of regenerating liver 3 antibody
  • Protein tyrosine phosphatase type IVA member 3 antibody
  • Protein tyrosine phosphatase type IVA protein 3 antibody
  • PTP 4A3 antibody
see all

Database links

Anti-PTP4A3 antibody images:

  Western blot - PTP4A3 antibody (ab26947)

Western blot - PTP4A3 antibody (ab26947)

All lanes : Anti-PTP4A3 antibody (ab26947) at 1/5000 dilution

Lane 1 : (T2.5) IPTG induction of the recombinant protein expression for 2.5 hours.
Lane 2 : (T0) before IPTG induction of the protein expression


Predicted band size : 19 kDa
Observed band size : 23.9 kDa (why is the actual band size different from the predicted?)

References for Anti-PTP4A3 antibody (ab26947)

This product has been referenced in:

  • Laurent C  et al. High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients. Cancer Res 71:666-74 (2011). WB; Human.Read more (PubMed: 21135111) »

See 1 publication for this product

Publishing research using ab26947? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"