PTPD2 peptide (ab12578)
- Product namePTPD2 peptideSee all PTPD2 proteins and peptides ...
Our Abpromise guarantee covers the use of ab12578 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
- Cytoskeletal associated protein tyrosine phosphatase
- Phosphatase with ezrin domain
- Protein tyrosine phosphatase non receptor type 14
- protein tyrosine phosphatase non-receptor type 14
- Protein tyrosine phosphatase pez
- Protein-tyrosine phosphatase pez
- PTP 36
- PTPD 2
- PTPN 14
- Tyrosine protein phosphatase non receptor type 14
- Tyrosine-protein phosphatase non-receptor type 14
- FunctionProtein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis.
- Tissue specificityExpressed in a variety of human tissues including kidney, skeletal muscle, lung and placenta.
- Involvement in diseaseDefects in PTPN14 are a cause of choanal atresia and lymphedema (CHATLY) [MIM:613611]. A disease characterized by posterior choanal atresia and lymphedema. Additional features are a high-arched palate, hypoplastic nipples, and mild pectus excavatum. Note=A homozygous deletion in PTPN14 predicted to result in frameshift and premature truncation, has been shown to be the cause of choanal atresia and lymphedema in one family.
- Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
Contains 1 FERM domain.
Contains 1 tyrosine-protein phosphatase domain.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
- Cellular localizationCytoplasm > cytoskeleton.
References for PTPD2 peptide (ab12578)
ab12578 has not yet been referenced specifically in any publications.