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Anti-Parvin alpha antibody (ab11336)

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Overview

Product name

Anti-Parvin alpha antibody
See all Parvin alpha products (4) ...

Description

Rabbit polyclonal to Parvin alpha

Tested applications

WB, ICC/IFmore details

Cross reactivity

Reacts with

Mouse, Human

Predicted to work with

Rat

Immunogen

Synthetic peptide: gtlarrkkakevsefqeeg conjugated to KLH, corresponding to amino acids 35-53 of Mouse Parvin alpha. The sequence is identical in human actopaxin and has considerable homology (70%) with beta parvin/affixin, but no homology with gamma parvin.

gtlarrkkakevsefqeeg

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

General notes

Storage in frost-free freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: 0.01M PBS, pH 7.4

Concentration

Concentration information loading...

Purity

IgG fraction

Purification notes

Whole antiserum is fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins.

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Binding Proteins
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> Structures >> Focal Adhesions

Applications

Show applications key

Our Abpromise guarantee covers the use of ab11336 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Members of the parvin family, including Parvin alpha (PARVA), are actin-binding proteins associated with focal contacts. Parvin alpha probably plays a role in the regulation of cell adhesion and cytoskeleton organization.

Cellular localization

Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note: Constituent of focal adhesions.

Alternative names

  • Actopaxin antibody
  • Alpha parvin antibody
  • Calponin like integrin linked kinase binding protein antibody
  • CH ILKBP antibody
  • FLJ10793 antibody
  • FLJ12254 antibody
  • Matrix remodelling associated 2 antibody
  • Matrix remodelling associated protein 2 antibody
  • MXRA 2 antibody
  • MXRA2 antibody
  • PARV A antibody
  • PARVA antibody
see all

Database links

References for Anti-Parvin alpha antibody (ab11336)

This product has been referenced in:

  • Birschmann I  et al. Use of functional highly purified human platelets for the identification of new proteins of the IPP signaling pathway. Thromb Res 122:59-68 (2008).Read more (PubMed: 17931695) »
  • Tucker KL  et al. A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion. Blood 112:4523-31 (2008). WB; Mouse.Read more (PubMed: 18772455) »

See all 3 publications for this product

Publishing research using ab11336? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"