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Perilipin A+B peptide (ab5010)

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Overview

Product name

Perilipin A+B peptide

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Concentration

Concentration information loading...

Sequence notes

An 18 amino acid synthetic peptide whose sequence is derived from rat perilipin A and B protein. The sequence of this peptide is (amino to carboxy terminus): M(1)SMNKGP TLLDGDLPEQ (17) - C.

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Adipose Related >> Lipid Droplet Protein

Applications

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Our Abpromise guarantee covers the use of ab5010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

This peptide can be used with studies using ab3527.

Protein info

Relevance

Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.

Cellular localization

Lipid droplet

References for Perilipin A+B peptide (ab5010)

ab5010 has not yet been referenced specifically in any publications.

Publishing research using ab5010? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"