|
|
|
|
|
Product Name
|
Perilipin A+B peptide
|
|
Product type
|
Proteins and Peptides
|
|
Tested applications
(see key)
|
BL
|
|
Research areas
|
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Adipose Related >> Lipid Droplet Protein
|
|
|
|
|
Relevance
|
Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells. There are currently two known isoforms, Perilipin A and B. Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and rat perilipin A and B, catalog ab3527. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.
|
|
|
|
|
Form
|
Liquid
|
|
Concentration
|
0.500 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
|
Sequence
|
An 18 amino acid synthetic peptide whose sequence is derived from rat perilipin A and B protein. The sequence of this peptide is (amino to carboxy terminus): M(1)SMNKGPTLLDGDLPEQ(17) - C.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Perilipin A+B peptide is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to Perilipin A+B
|
| |
Perilipin A+B peptide - more information
|
Customer reviews (feedback) regarding Perilipin A+B peptide |
Customer FAQs regarding Perilipin A+B peptide |
Protocols for Perilipin A+B peptide |
Price and availability of products related to Perilipin A+B peptide |
| |
Perilipin A+B peptide - related products:
|
|
|
| |
Perilipin A+B peptide - other tools:
|
Contact Abcam with a Technical Enquiry about Perilipin A+B peptide |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
