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Products:Cardiovascular >> Lipids / Lipoproteins >> Adipose Related >> Lipid Droplet Protein
Overview
Product name
Perilipin A peptide
See all Perilipin A products (2) ...
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Concentration
Concentration information loading...
Sequence notes
A 17 amino acid synthetic peptide whose sequence is derived from rat perilipin A protein. The sequence of this peptide is (amino to carboxy terminus): C - E(502 )PILGRTQYS QLRKKS(517 ).
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cardiovascular >> Atherosclerosis >> Lipoprotein metabolism
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Adipose Related >> Lipid Droplet Protein
Applications
Show applications key
Our Abpromise guarantee covers the use of ab5009 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
BL: Use at an assay dependent concentration.
Application notes
This peptide can be used with studies using ab3526.
Protein info
Function
Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness.
Tissue specificity
Adipocytes.
Sequence similarities
Belongs to the perilipin family.
Post-translational
modifications
Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet.
Cellular localization
Lipid droplet. Lipid droplet surface-associated.
Target information above from: UniProt accessionO60240
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for Perilipin A peptide (ab5009)
ab5009 has not yet been referenced specifically in any publications.
Publishing research using ab5009? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"