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IHC-P - Peroxiredoxin 1 antibody (ab58252)
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Western blot - Peroxiredoxin 1 antibody (ab58252)
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Product Name
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Peroxiredoxin 1 antibody
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See all Peroxiredoxin 1 antibodies (9)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to Peroxiredoxin 1
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Immunogen
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Recombinant full length protein, corresponding to amino acids 1-200 of Human Peroxiredoxin 1
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic
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Research areas
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Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Inflammatory mediators
Cell Biology >> Other Antibodies >> Other Antibodies
Cell Biology >> Other Antibodies >> Oxidative Stress
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Relevance
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Peroxiredoxin 1 is involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It is constitutively expressed in most human cells; is induced to higher levels upon serum stimulation in untransformed and transformed cells.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Peroxiredoxin 1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Peroxiredoxin 1 antibody images:
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 IHC-P - Peroxiredoxin 1 antibody (ab58252)
Peroxiredoxin 1 antibody (ab58252) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human tonsil tissue.
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Western blot - Peroxiredoxin 1 antibody (ab58252)
Predicted band size : 22 kDa
Peroxiredoxin 1 antibody (ab58252) at 1ug/lane + HeLa cell lysate at 25ug/lane.
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References for Peroxiredoxin 1 antibody (ab58252)
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This product has been used in:
Myers CR & Myers JM The effects of acrolein on peroxiredoxins, thioredoxins, and thioredoxin reductase in human bronchial epithelial cells. Toxicology 257:95-104 (2009). PubMed: 19135121
If you publish research using ab58252 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to Peroxiredoxin 1
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Peroxiredoxin 1 antibody - more information
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Customer reviews (feedback) regarding Peroxiredoxin 1 antibody |
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Protocols for Peroxiredoxin 1 antibody |
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Peroxiredoxin 1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about Peroxiredoxin 1 antibody |
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