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Immunocytochemistry - Peroxiredoxin 4 antibody (ab15574)
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Product Name
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Peroxiredoxin 4 antibody
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See all Peroxiredoxin 4 antibodies (6)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Peroxiredoxin 4
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Immunogen
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Antigen is purified human recombinant Peroxiredoxin 4 from K562 cells.
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Reacts with
(species key)
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Hu
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Specificity
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This antibody is specific for Peroxiredoxin 4 and shows no cross reactivity with other Peroxiredoxin isoforms.
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Tested applications
(see key)
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ICC/IF, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ICC: 1/500.
WB: 1/10000. Detects a band of approximately 23 kDa and 20 kDa representing Pro-Peroxiredoxin 4 and mature Peroxiredoxin 4 respectively (predicted molecular weight: 33 kDa).
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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PC3 cell lysate (WB)
TSU-Pr1 cells (ICC)
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Cellular localization
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Cytoplasmic
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Research areas
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Cell Biology >> Other Antibodies >> Other Antibodies
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Relevance
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The Peroxiredoxin (Prdx, Prx, or TrxPx) family of enzymes is a recently identified family of peroxidases found in free living organisms. The six known isoforms (Prx1 to 6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer.
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Peroxiredoxin 4 antibody (ab15574) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: 0.05% Sodium Azide
Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Peroxiredoxin 4 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for Peroxiredoxin 4 antibody images, references, products related to ab15574 and other tools.
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Peroxiredoxin 4 antibody images:
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 Immunocytochemistry - Peroxiredoxin 4 antibody (ab15574)
ab15574 staining Peroxiredoxin 4 in TSU-Pr1 cells.
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Search PubMed (MEDLINE) for references to Peroxiredoxin 4
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Peroxiredoxin 4 antibody - more information
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Customer reviews (feedback) regarding Peroxiredoxin 4 antibody |
Customer FAQs regarding Peroxiredoxin 4 antibody |
Protocols for Peroxiredoxin 4 antibody |
Price and availability of products related to Peroxiredoxin 4 antibody |
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Peroxiredoxin 4 antibody - related products:
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Peroxiredoxin 4 antibody - other tools:
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Contact Abcam with a Technical Enquiry about Peroxiredoxin 4 antibody |
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