Phentolamine hydrochloride, Non-selective alpha antagonist (ab120791)
Key features and details
- Non-selective α antagonist
- CAS Number: 73-05-2
- Purity: > 98%
- Soluble in water to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Phentolamine hydrochloride, Non-selective alpha antagonist -
Description
Non-selective α antagonist -
Purity
> 98% -
CAS Number
73-05-2 -
Chemical structure
Properties
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Chemical name
3-[[(4,5-Dihydro-1-imidazol-2-yl)methyl](4-methylphenyl)amino]phenol hydrochloride -
Molecular weight
317.81 -
Molecular formula
C17H19N3O.HCl -
PubChem identifier
5702144 -
Storage instructions
Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. -
Solubility overview
Soluble in water to 50 mM -
Handling
Unstable; make up solutions fresh and use immediately.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.Cl -
Source
Synthetic
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Research areas
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (5)
ab120791 has been referenced in 5 publications.
- Wang M et al. Regulation of Spontaneous Contractions in Intact Rat Bladder Strips and the Effects of Hydrogen Peroxide. Biomed Res Int 2018:2925985 (2018). PubMed: 29511675
- Byrne AM et al. The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration. Redox Biol 10:128-139 (2016). PubMed: 27744118
- Zhang Q & Tan Y Nerve growth factor augments neuronal responsiveness to noradrenaline in cultured dorsal root ganglion neurons of rats. Neuroscience 193:72-9 (2011). PubMed: 21784134
- Ahn SW et al. Phentolamine inhibits the pacemaker activity of mouse interstitial cells of Cajal by activating ATP-sensitive K+ channels. Arch Pharm Res 33:479-89 (2010). PubMed: 20361315
- Proks P & Ashcroft FM Phentolamine block of KATP channels is mediated by Kir6.2. Proc Natl Acad Sci U S A 94:11716-20 (1997). PubMed: 9326676