Overview

  • Product nameAnti-Phospholipase A2 X antibodySee all Phospholipase A2 X primary antibodies ...
  • Description
    Rabbit polyclonal to Phospholipase A2 X
  • SpecificityThis antibody is specific for Phospholipase A2 X.
  • Tested applicationsELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human Phospholipase A2 X. A 15.5 kDa protein containing 123 amino acid residues of the human Phospholipase A2 X and 16 additional amino acid residues, HisTag. Source of immunogen, E.coli

Properties

Applications

Our Abpromise guarantee covers the use of ab47111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 17 kDa.

Target

  • FunctionPA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids. Prefers phosphatidylethanolamine and phosphatidylcholine liposomes to those of phosphatidylserine.
  • Tissue specificityFound in spleen, thymus, peripheral blood leukocytes, pancreas, lung, and colon.
  • Sequence similaritiesBelongs to the phospholipase A2 family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Group 10 secretory phospholipase A2 antibody
    • Group X secretory phospholipase A2 antibody
    • GX sPLA2 antibody
    • GXPLA2 antibody
    • GXSPLA2 antibody
    • PA2GX_HUMAN antibody
    • Phosphatidylcholine 2 acylhydrolase GX antibody
    • Phosphatidylcholine 2-acylhydrolase 10 antibody
    • Phospholipase A2 group X antibody
    • PLA2G10 antibody
    • SPLA2 antibody
    • sPLA2-X antibody
    • sPLA2X antibody
    see all

Anti-Phospholipase A2 X antibody images

  • All lanes : Anti-Phospholipase A2 X antibody (ab47111) at 1 µg/ml

    Lane 1 : Whole cell extracts from RAW264.7 control cells
    Lane 2 : Whole cell extracts from RAW264.7 cells overexpressing Phospholipase A2 X

    Lysates/proteins at 20 µg per lane.

    Secondary
    Horseradish peroxidase-conjugated secondary antibody

    Predicted band size : 17 kDa
    Observed band size : 17 kDa

    Image from Curfs DM et al, J Biol Chem. 2008 Aug 1;283(31):21640-8. Epub 2008 May 28, Fig 1.DOI 10.1074/jbc.M710584200

References for Anti-Phospholipase A2 X antibody (ab47111)

This product has been referenced in:
  • Curfs DM  et al. Macrophage Secretory Phospholipase A2 Group X Enhances Anti-inflammatory Responses, Promotes Lipid Accumulation, and Contributes to Aberrant Lung Pathology. J Biol Chem 283:21640-8 (2008). WB ; Human . Read more (PubMed: 18511424) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"