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Product Name
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Phospholipase A2 XII antibody
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See all Phospholipase A2 XII antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Phospholipase A2 XII
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Immunogen
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Recombinant human Phospholipase A2 XII. 20.6 kDa protein containing 167 amino acid residues of the human Phospholipase A2 XII and 16 additional amino acid residues, HisTag. Source of immunogen E.coli
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Reacts with
(species key)
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Hu
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Specificity
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This antibody is specific for Phospholipase A2 XII.
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Lipases
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Relevance
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Phospholipase A2 catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid, a precursor of eicosanoids including prostaglandins and leukotrienes.
This enzyme has been proposed to hydrolyze phosphatidylcholine (PC) in lipoproteins to liberate lyso-PC and free fatty acids in the arterial wall, thereby facilitating the accumulation of bioactive lipids and modified lipoproteins in atherosclerotic foci.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: None
Constituents: 0.1M Sodium chloride, 0.05M Phosphate, pH 7.2
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Purification notes
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Immunoaffinity chromatography on a column with immobilized recombinant
human Phospholipase A2 XII.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Phospholipase A2 XII antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Phospholipase A2 XII
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