Phosphotyrosine antibody (ab45287)

Product Name 

Phosphotyrosine antibody

Product type 

Primary antibodies

Description 

Mouse monoclonal to Phosphotyrosine

Immunogen 

Phosphotyrosine.

Predicted to react 
(species key)

Hu, Ms, Rat
(Due to sequence homology)

Tested applications 
(see key)

IP, WB

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
IP: Use at an assay dependent dilution.
WB: 1/1000.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Signal Transduction >> Protein Phosphorylation >> Tyrosine Phosphatases
Signal Transduction >> Metabolism >> Amino Acids
Neuroscience >> Neurotransmission >> Intracellular Signaling >> Phosphatases

Relevance 

The phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine phosphorylated proteins and the biochemical pathways in which they function.

Raised in 

Mouse

Clonality 

Monoclonal

Isotype 

IgG

Purity 

Protein A purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS

Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS

Form 

Liquid

Concentration 

0.500 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

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