Piccolo peptide (ab23400)

Product Name 

Piccolo peptide

Product type 

Proteins and Peptides

Peptide 

Synthetic peptide derived from within residues 600 - 700 of Rat Piccolo.


This peptide was used as an immunogen for ab30595.

Research areas 

Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker

Relevance 

Piccolo is a presynaptic cytomatrix protein concentrated at the presynaptic side of synaptic junctions. Piccolo is a large protein which constists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains (PBH-domains) and C-terminal PDZ and C2 domains. It is usually found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Recently piccolo has been shown to interfere with clathrin mediated endocytosis by binding to the F-actin and dynamin binding protein Abp1. Piccolo is highly expressed in brain with low levels found in stomach. It is not detected in other tissues analyzed including adrenal gland, testis and pancreas.

Storage buffer 

Preservative: None
Constituents: 0.001% Tween 20, HEPES, 2mM EDTA, 150mM Sodium chloride

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Customer reviews (feedback) regarding Piccolo peptide

Customer FAQs regarding Piccolo peptide

Protocols for Piccolo peptide

Price and availability of products related to Piccolo peptide

Piccolo peptide - related products: