Pifithrin-α-HBr is light senstive and it is recommended that the compound is protected from light.
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
References for Pifithrin-α-HBr (ab120478)
This product has been referenced in:
- Sohn D et al. Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53. Cell Death Differ 16:869-78 (2009). Read more (PubMed: 19229248) »
- Hoagland MS et al. The p53 inhibitor pifithrin-alpha is a potent agonist of the aryl hydrocarbon receptor. J Pharmacol Exp Ther 314:603-10 (2005). Read more (PubMed: 15843497) »
- Komarova EA et al. p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways. J Biol Chem 278:15465-8 (2003). Read more (PubMed: 12637507) »
- Komarov PG et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285:1733-7 (1999). Read more (PubMed: 10481009) »