AbcamBiochemicals

Pindolol Fluorescent ligand (Red) (ab118170)

Overview

  • Product namePindolol Fluorescent ligand (Red)
  • Description

    Fluorescent β2 antagonist

  • Alternative names
    • ß3-633-AN4
  • Biological descriptionFluorescent β2 antagonist (pKD values are 7.01, 7.96 and 6.42 at β1, β2 and β3 respectively). Wide range of applications which include localizing receptor distribution in tissues and cells, and live-cell imaging of receptor kinetics. Intrinsic, weak partial agonist activity at β1, β2 and β3 receptors (SEAP reporter gene assay).

    Excitation wavelength: 633 nm

    Emission wavelength: 650 nm

  • Purity> 97%

Properties

    Applications

    Our Abpromise guarantee covers the use of ab118170 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Small Molecule Fluorescent Optical Detection Use at an assay dependent concentration.
    Receptor Localization Use at an assay dependent concentration.
    Fluorescent Cell Imaging Use at an assay dependent concentration.

    Pindolol Fluorescent ligand (Red) images

    • ab118170 ligand binding and displacement.
      Top (a, C): ab118170 binding to two different live cell lines expressing β1 (A) or β2 (C) adrenoceptors.
      Bottom (B, D): Binding blocked in the same two cell lines β1 (B) or β2 (D) by the unlabelled competitor ICI118551 (1 µM).
      Nuclei have been counter-stained with Hoechst.

    References for Pindolol Fluorescent ligand (Red) (ab118170)

    ab118170 has not yet been referenced specifically in any publications.

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    I am sorry to confirm that as far as we are aware,the fluorescent ligandshave not been tested in flow cytometry. All tested and guaranteed applications are specified on our d...

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    The product can be dissolved to 10 mM or 1 mM (to give a larger volume) in DMSO.

    · Appropriate final DMSO concentration is 0.1% (in buffer)

    · We are not aware of aqueous solubility o...

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