Pindolol, 5-HT1A and 5-HT1B receptor antagonist (ab120521)
Key features and details
- 5-HT1A and 5-HT1B receptor antagonist
- CAS Number: 13523-86-9
- Soluble in DMSO to 50 mM and in ethanol to 25 mM (with heating)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Pindolol, 5-HT1A and 5-HT1B receptor antagonist -
Description
5-HT1A and 5-HT1B receptor antagonist -
Biological description
5-HT1A and 5-HT1B receptor antagonist (Ki and IC50 values are 8.9 and 6.8 nM at 5-HT1A and 5-HT1B receptors, respectively). Partial β3 adrenoceptor agonist (pEC50 = 5.11). Accelerates antidepressant effects of selective serotonin reuptake inhibitors (SSRIs).
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CAS Number
13523-86-9 -
Chemical structure
Properties
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Chemical name
1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol -
Molecular weight
248.32 -
Molecular formula
C14H20N2O2 -
PubChem identifier
4828 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 50 mM and in ethanol to 25 mM (with heating) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)NCC(O)COc2cccc1nccc12 -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab120521 has not yet been referenced specifically in any publications.