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Product Name 

Plasma Kallikrein 1B antibody - Apple Domain 2

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to Plasma Kallikrein 1B - Apple Domain 2

Immunogen 

(Peptide available as ab43117.)

Reacts with 
(species key)

Hu, Ms, Rat

Specificity 

ab43084 recognizes the zymogen form of plasma kallikrein and the heavy chain of factor XIIa cleaved plasma kallikrein, but not the kallikrein heavy chain, and can be used to distinguish the two forms.

We have a range of domain specific antibodies for this target. For a full list please see all Plasma Kallikrein 1B antibodies

Tested applications 
(see key)

WB


Abreviews 

Customer reviews
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WB
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Application notes 
(see key)

Recommended dilutions
WB: 1:1000. Predicted molecular weight: 71 kDa. A 1:5000 dilution is recommended for chemiluminescent substrates. Higher concentrations of antibody may be needed for samples from more distantly related species. EDTA/EGTA treatment of tissues or lysates is required to see latent zymogen. Glycosylation and other post translational modifications give plasma kallikrein a higher apparent molecular weights of 88 and 85 kDa Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.



Specific protocols
Recommended WB protocol

Cellular localization 

Secreted

Research areas 

Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Serine protease >> Kallikreins

Relevance 

Plasma Kallikrein 1B is a serine proteinase of the S1 family It is secreted by the liver, kidney, adrenal gland and placenta. The zymogen is referred to as prekallikrein (PK) and is activated by Factor XIIa to an active two chain form, plasma kallikrein. In Fletcher syndrome plasma kallikrein is deficient, resulting in a prolonged partial thromboplastin time (PT).

 

Alternative names Plasma Kallikrein 1B antibody - Apple Domain 2 (ab43084)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

3818    (Human)
16621    (Mouse)
25048    (Rat)

Omim

    

229000    (Human)

SwissProt

    

P03952    (Human)
P26262    (Mouse)
P14272    (Rat)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.5% Sodium Azide
Constituents: 50% Glycerol

Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS

Purification notes 

Peptide-affinity purified.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

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Search PubMed (MEDLINE) for references to Plasma Kallikrein 1B

 

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Plasma Kallikrein 1B antibody - Apple Domain 2 - related products:

Products for Western blot

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Lysates

 

Immunizing Peptide for Plasma Kallikrein 1B antibody - Apple Domain 2

ab43117

  

Plasma Kallikrein 1B peptide (Apple Domain 2)

 

Compatible Secondaries for Plasma Kallikrein 1B antibody - Apple Domain 2

ab6564

  

Cy5 ® antibody

ab6717

  

FITC antibody

ab6720

  

Biotin antibody

ab6721

  

HRP antibody

ab6722

  

Alkaline Phosphatase antibody

ab6793

  

Texas Red ® antibody

ab7007

  

Phycoerythrin antibody

ab7019

  

Agarose antibody

ab27234

  

10nm Gold antibody

ab27235

  

5nm Gold antibody

ab27236

  

15nm Gold antibody

ab27237

  

20nm Gold antibody

ab27238

  

30nm Gold antibody

ab27239

  

10nm Gold antibody

ab27240

  

5nm Gold antibody

ab31193

  

Duck polyclonal to Rabbit IgG

ab60314

  

Chromeo™ 488 antibody

ab60315

  

Chromeo™ 494 antibody

ab60317

  

Chromeo™ 546 antibody

ab60319

  

Chromeo™ 642 antibody

 

Other Plasma Kallikrein 1B Antibodies

See all Plasma Kallikrein 1B antibodies (5)...

 

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