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Anti-Plasmodium falciparum MSP1 antibody [PEM-1] (ab38751)

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2 questions for ab38751

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Question 1

Friday 27-January-2012

I am using the following antibodies against a part of Plasmodium falciparum MSP1 protein in Western blot:
[B937P] (ab38252)
[PEM-1] (ab38751)

I was wondering if you have any information about the epitopes of these two antibodies?
Moreover, do you know if they bind native and/or denatured form of the protein?

ANSWER:

  

Thank you for contacting us.

Regarding the anti-Plasmodium falciparum MSP1 antibody, clone B937P, we are still waiting for the originating laboratory to provide the location of the epitope, if mapped. The same question was asked in 2007 by another customer and at that time, the location of the epitope was unknown. I have also asked if it is known to bind the native and/or denatured form of the protein and will forward this information when I receive it.

For the other antibody you asked about, anti-Plasmodium falciparum MSP1 antibody, clone PEM-1, the originating laboratory reports that they have tested this antibody only with recombinant protein produced in E. coli under reducing and denaturing conditions. Again, the location of the epitope the antibody binds to is unknown.

Question 2

Tuesday 06-November-2007

What is the size of the protein detected, as Plasmodium falciparum MSP1 is cleaved in several fragments?

ANSWER:

  

I have received today feedback regarding ab38751, and was informed that western blotting was not tested by the originating laboratory, but they have feedback from several of their customers that they have successfully used the product in WB. This is the reason why this application is mentioned in our data sheet. Unfortunately we don't have the results from these customers so we are unfortunately unable to answer your question.

I'm sorry I am unable to provide further information regarding this product. I am still waiting for details regarding ab38252, thank you for your patience.

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