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Overview

  • Product namePrazosin hydrochloride
  • Description
    α-adrenoceptor antagonist. Melatonin antagonist.
  • Biological descriptionPeripheral α1- and α2-adrenoceptor antagonist. Orally active vasodilator. Also melatonin MT3 antagonist.
  • Purity> 99%

    • Properties

  • Chemical name[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanylmethanone hydrochloride
  • Molecular Weight419.86
  • Chemical structureChemical Structure
  • Molecular formulaC19H21N5O4.HCl
  • CAS Number19237-84-4
  • PubChem identifier68546
  • Storage instructionsStore at +4°C (desiccating conditions).
  • Solubility overviewSoluble in DMSO to 25 mM (with warming)
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • SMILESCl.O=C(N1CCN(CC1)c3nc2cc(OC)c(OC)cc2c(N)n3)c4ccco4
  • Source

    Synthetic

  • Research Areas

    • References for Prazosin hydrochloride (ab120238)

    This product has been referenced in:
    • Pickering DS & Niles LP 2-[125I]iodomelatonin binding sites in hamster and chick exhibit differential sensitivity to prazosin. J Pharm Pharmacol 41:356-7 (1989). Read more (PubMed: 2569529) »
    • Stanaszek WF  et al. Prazosin update. A review of its pharmacological properties and therapeutic use in hypertension and congestive heart failure. Drugs 25:339-84 (1983). Read more (PubMed: 6303744) »
    • Battaglia G  et al. Properties of [3H]prazosin-labeled alpha 1-adrenergic receptors in rat brain and porcine neurointermediate lobe tissue. J Neurochem 41:538-42 (1983). Read more (PubMed: 6308163) »

    See 1 Publication for this product

    Publishing research using ab120238 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"