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Product Name
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Pregnancy Specific Glycoprotein 1 antibody [BAP3]
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See all Pregnancy Specific Glycoprotein 1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [BAP3] to Pregnancy Specific Glycoprotein 1
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Immunogen
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Ab26284 was generated by immunization of BALB/c mice with purified human Pregnancy Specific Glycoprotein 1 isolated from retroplacental blood.
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Reacts with
(species key)
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Hu
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Specificity
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ab26284 recognizes an epitope in the B2 domain which is present in most (PSG1, PSG3, PSG4, PSG5, PSG9 and PSG11) if not all human PSG. It does not cross-react significantly with any of the CEACAM subgroup members of the CEA family (CEACAM 1, CEACAM 3, CEACAM 4, CEACAM5/CEA, CEACAM6, CEACAM7 and CEACAM8).
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Tested applications
(see key)
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Flow Cyt, IHC-Fr
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Tags & Cell Markers >> Cell Type Markers >> Other Cell Types
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Relevance
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Pregnancy Specific Glycoprotein 1 reacts with human pregnancy-specific glycoproteins (PSG), a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarcinoma). They represent the most abundant fetal protein in the maternal blood at term. The eleven human PSG genes (PSG1-PSG11) form together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes the CEACAM gene family. PSG stimulate secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17. PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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BAP3
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Isotype
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IgG1
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.01% Sodium Azide
Constituents: PBS, pH 7.2 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Pregnancy Specific Glycoprotein 1 antibody [BAP3] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Pregnancy Specific Glycoprotein 1
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Pregnancy Specific Glycoprotein 1 antibody [BAP3] - more information
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Customer reviews (feedback) regarding Pregnancy Specific Glycoprotein 1 antibody [BAP3] |
Customer FAQs regarding Pregnancy Specific Glycoprotein 1 antibody [BAP3] |
Protocols for Pregnancy Specific Glycoprotein 1 antibody [BAP3] |
Price and availability of products related to Pregnancy Specific Glycoprotein 1 antibody [BAP3] |
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Pregnancy Specific Glycoprotein 1 antibody [BAP3] - related products:
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Pregnancy Specific Glycoprotein 1 antibody [BAP3] - other tools:
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Contact Abcam with a Technical Enquiry about Pregnancy Specific Glycoprotein 1 antibody [BAP3] |
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