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Product Name
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Pregnancy Specific Glycoprotein 1 antibody
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See all Pregnancy Specific Glycoprotein 1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Pregnancy Specific Glycoprotein 1
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Immunogen
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Full length native Pregnancy Specific Glycoprotein 1 protein purified from Human.
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Reacts with
(species key)
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Hu
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Specificity
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This antibody is specific for human Pregnancy Specific Glycoprotein 1.
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Tested applications
(see key)
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ELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions ELISA (50%B): 1/750. ELISA (EPT): 1/35000.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Tags & Cell Markers >> Cell Type Markers >> Other Cell Types
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Relevance
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Pregnancy Specific Glycoprotein 1 reacts with human pregnancy-specific glycoproteins (PSG), a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarcinoma). They represent the most abundant fetal protein in the maternal blood at term. The eleven human PSG genes (PSG1-PSG11) form together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes the CEACAM gene family. PSG stimulate secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17. PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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IgG fraction
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Storage buffer
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Preservative: 0.1% Sodium Azide Constituents: PBS, pH 7.2 Material safety datasheet (MSDS) for this product: Sodium Azide MSDS
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Purification notes
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Ammonium sulfate fractionation.
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Form
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Liquid
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Concentration
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0.900 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Pregnancy Specific Glycoprotein 1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Pregnancy Specific Glycoprotein 1
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Pregnancy Specific Glycoprotein 1 antibody - more information
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