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Product Name 

Pregnancy Specific Glycoprotein 1 antibody

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to Pregnancy Specific Glycoprotein 1

Immunogen 

Full length native Pregnancy Specific Glycoprotein 1 protein purified from Human.

Reacts with 
(species key)

Hu

Specificity 

This antibody is specific for human Pregnancy Specific Glycoprotein 1.

Tested applications 
(see key)

ELISA


Abreviews 

Customer reviews
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Application notes 
(see key)

Recommended dilutions
ELISA (50%B): 1/750.
ELISA (EPT): 1/35000.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Secreted

Research areas 

Tags & Cell Markers >> Cell Type Markers >> Other Cell Types

Relevance 

Pregnancy Specific Glycoprotein 1 reacts with human pregnancy-specific glycoproteins (PSG), a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarcinoma). They represent the most abundant fetal protein in the maternal blood at term. The eleven human PSG genes (PSG1-PSG11) form together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes the CEACAM gene family. PSG stimulate secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17. PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection.

 

Alternative names Pregnancy Specific Glycoprotein 1 antibody (ab35098)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

5669    (Human)

Omim

    

176390    (Human)

SwissProt

    

P11464    (Human)

Unigene

    

709192    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

IgG fraction

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.2

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Ammonium sulfate fractionation.

Form 

Liquid

Concentration 

0.900 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Pregnancy Specific Glycoprotein 1 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

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