Anti-Progesterone antibody [11P14] (ab20236)
Key features and details
- Mouse monoclonal [11P14] to Progesterone
- Suitable for: RIA
- Reacts with: Human
- Isotype: IgG2b
Overview
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Product name
Anti-Progesterone antibody [11P14]
See all Progesterone primary antibodies -
Description
Mouse monoclonal [11P14] to Progesterone -
Host species
Mouse -
Tested applications
Suitable for: RIAmore details -
Species reactivity
Reacts with: Human -
Immunogen
11a-Hydroxyprogesterone conjugated to bovine serum albumin.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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Purity
Protein A/G purified -
Clonality
Monoclonal -
Clone number
11P14 -
Myeloma
P3-NS1/1-Ag4-1 -
Isotype
IgG2b -
Light chain type
unknown -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab20236 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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RIA |
Use at an assay dependent concentration.
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Notes |
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RIA
Use at an assay dependent concentration. |
Target
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Relevance
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Progesterone receptor, a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone. The PGR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. Although PRA and PRB share several structural domains, they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap. It is composed of three domains: a modulating N terminal domain, a DNA binding domain and a C terminal steroid binding domain. Progesterone levels 1. men 30-60 pg/0.1ml 2. women pre ovulatory phase: 20-160 pg/0.1ml; ovulatory phase: 1,000-1,700 pg/0.1ml; post ovulatory phase: 1,000-1,700 pg/0.1ml; Pregnant: 16-18 weeks: 300-800 pg/0.1ml; 28-30 weeks: 6,500-14,700 pg/0.1ml; 38-40 weeks: 12,000-19,000 pg/0.1ml. -
Cellular localization
Secreted -
Alternative names
- Pregn 4 ene 3 20 dione antibody
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab20236 has been referenced in 1 publication.
- Fantl VE et al. The production of high affinity monoclonal antibodies to progesterone. J Steroid Biochem 17:125-30 (1982). PubMed: 7109599