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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Prolactin Receptor antibody [B6.2] - BSA and Azide free (ab80565)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Prolactin Receptor antibody [B6.2] - BSA and Azide free (ab80565)](/ps/datasheet/images/80/ab80565/Prolactin-Primary-antibodies-ab80565-1.JPG)
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Product Name
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Prolactin Receptor antibody [B6.2] - BSA and Azide free
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See all Prolactin Receptor antibodies (8)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [B6.2] to Prolactin Receptor - BSA and Azide free
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Immunogen
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Semi-purified human Prolactin Receptor.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: Use at a concentration of 1 - 2 µg/ml (for 30 minutes at room temperature). Staining of formalin/paraffin tissues requires digestion of tissue sections with pepsin at 1 mg/ml (in Tris-HCl, pH 2.0 for 15 minutes at room temperature or 10 minutes at 37 °C).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Breast carcinoma
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Cellular localization
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Plasma Membrane; Single-pass type I membrane protein. Secreted
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Research areas
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Signal Transduction >> Metabolism >> Lipid metabolism
Signal Transduction >> Growth Factors/Hormones >> Hormones
Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Receptor Tyrosine Kinases
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Relevance
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Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor) which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription. Three isoforms of Prolactin receptor have been identified.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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B6.2
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Isotype
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IgG1
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
Constituents: 10mM PBS, pH 7.4
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Purification notes
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Purified from ascites fluid.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Prolactin Receptor antibody [B6.2] - BSA and Azide free is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for Prolactin Receptor antibody [B6.2] - BSA and Azide free images, references, products related to ab80565 and other tools.
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Prolactin Receptor antibody [B6.2] - BSA and Azide free images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Prolactin Receptor antibody [B6.2] - BSA and Azide free (ab80565)
Formalin fixed, paraffin embedded human breast cancer stained with ab80565 at 2 µg/ml. Peroxidase conjugate and AEC chromogen were used. Note cell membrane and cytoplasmic staining of tumor cells.
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Search PubMed (MEDLINE) for references to Prolactin Receptor
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Prolactin Receptor antibody [B6.2] - BSA and Azide free - more information
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Customer reviews (feedback) regarding Prolactin Receptor antibody [B6.2] - BSA and Azide free |
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Prolactin Receptor antibody [B6.2] - BSA and Azide free - related products:
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Prolactin Receptor antibody [B6.2] - BSA and Azide free - other tools:
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Contact Abcam with a Technical Enquiry about Prolactin Receptor antibody [B6.2] - BSA and Azide free |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Prolactin Receptor antibody [B6.2] - BSA and Azide free (ab80565)](/index.html?datasheet=80565#Prolactin-Primary-antibodies-ab80565-1.JPG)
