Anti-Proprotein Convertase 2 antibody (ab85261)

Overview

  • Product name
    Anti-Proprotein Convertase 2 antibody
    See all Proprotein Convertase 2 primary antibodies
  • Description
    Rabbit polyclonal to Proprotein Convertase 2
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from an internal region of Human Proprotein Convertase 2 conjugated to KLH (NP_002585).

  • Positive control
    • K-562 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85261 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 72 kDa (predicted molecular weight: 70 kDa).
ELISA 1/1000.

Target

  • Function
    Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues.
  • Sequence similarities
    Belongs to the peptidase S8 family. Furin subfamily.
  • Cellular localization
    Cytoplasmic vesicle > secretory vesicle. Localized in the secretion granules.
  • Information by UniProt
  • Database links
  • Alternative names
    • KEX2 like endoprotease 2 antibody
    • KEX2-like endoprotease 2 antibody
    • NEC 2 antibody
    • NEC2 antibody
    • NEC2_HUMAN antibody
    • Neuroendocrine convertase 2 antibody
    • PC2 antibody
    • PCSK2 antibody
    • Prohormone convertase 2 antibody
    • Proprotein convertase 2 antibody
    • Proprotein convertase subtilisin/kexin type 2 antibody
    • SPC2 antibody
    see all

Images

  • Anti-Proprotein Convertase 2 antibody (ab85261) at 1/50 dilution + K-562 cell line lysates at 35 µg

    Predicted band size : 70 kDa
    Observed band size : 72 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 28 kDa. We are unsure as to the identity of these extra bands.

References

ab85261 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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