Overview
- Product nameAnti-Proprotein Convertase 2 antibodySee all Proprotein Convertase 2 primary antibodies ...
- DescriptionRabbit polyclonal to Proprotein Convertase 2
- Tested applicationsWB, ELISA more details
- Species reactivityReacts with: Human
- Immunogen
Synthetic peptide selected from an internal region of Human Proprotein Convertase 2 conjugated to KLH (NP_002585).
- Positive controlK-562 cell line lysate.
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferPreservative: 0.09% Sodium Azide
Constituents: PBS -
Concentration information loading... - PurityAmmonium Sulphate Precipitation
- Purification notesab85261 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab85261 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/50 - 1/100. Detects a band of approximately 72 kDa (predicted molecular weight: 70 kDa). |
| ELISA | ELISA: 1/1000. |
Target
- FunctionInvolved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues.
- Sequence similaritiesBelongs to the peptidase S8 family. Furin subfamily.
- Cellular localizationCytoplasmic vesicle > secretory vesicle. Localized in the secretion granules.
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Database links
- Entrez Gene: 5126 Human
- Entrez Gene: 5126 Human
- Omim: 162151 Human
- SwissProt: P16519 Human
- SwissProt: P16519 Human
- Unigene: 315186 Human
Target information above from: UniProt accession
P16519
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- KEX2 like endoprotease 2 antibodyKEX2-like endoprotease 2 antibodyNEC 2 antibody
- NEC2 antibodyNEC2_HUMAN antibodyNeuroendocrine convertase 2 antibodyPC2 antibodyPCSK2 antibodyProhormone convertase 2 antibodyProprotein convertase 2 antibodyProprotein convertase subtilisin/kexin type 2 antibodySPC2 antibody
see all
Anti-Proprotein Convertase 2 antibody images
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Western blot - Proprotein Convertase 2 antibody (ab85261)Anti-Proprotein Convertase 2 antibody (ab85261) at 1/50 dilution + K-562 cell line lysates at 35 µg
Predicted band size : 70 kDa
Observed band size : 72 kDa (why is the actual band size different from the predicted?)
Additional bands at : 28 kDa. We are unsure as to the identity of these extra bands.
References for Anti-Proprotein Convertase 2 antibody (ab85261)
ab85261 has not yet been referenced specifically in any publications.
