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Products:Neuroscience >> Cell Adhesion Proteins >> Proteases
Overview
Product name
Anti-Prostate Specific Antigen antibody [A67-B/E3]
See all Prostate Specific Antigen products (32) ...
Description
Mouse monoclonal [A67-B/E3] to Prostate Specific Antigen
Specificity
This antibody is specific for PSA.
Tested applications
ELISA, IHC-P, WBmore details
Cross reactivity
Reacts with
Human
Immunogen
Tissue / cell preparation (Human). 30 kDa protein fraction prepared from human seminal plasma.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 15mM Sodium Azide
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
>95% by SDS-PAGE
Purification notes
Purified from ascites using precipitation methods.
Clonality
Monoclonal
Clone number
A67-B/E3
Myeloma
unknown
Isotype
IgG1
Light chain type
unknown
Research areas
Cancer >> Tumor biomarkers >> Tumor antigens
Cancer >> Tumor immunology >> Tumor-associated antigens
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> Kallikreins
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Neuroscience >> Cell Adhesion Proteins >> Proteases
Applications
Show applications key
Our Abpromise guarantee covers the use of ab2218 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
IHC-P
WB
Application notes
ELISA: Use at an assay dependant dilution.
IHC-P: Use at an assay dependant dilution. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
WB: Use at an assay dependant dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Sequence similarities
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.
Cellular localization
Secreted.
Target information above from: UniProt accessionP07288
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- APS antibody
- Gamma seminoprotein antibody
- Gamma-seminoprotein antibody
see all
Database links
- Entrez Gene: 354 Human
- Omim: 176820 Human
- SwissProt: P07288 Human
- Unigene: 171995 Human
References for Anti-Prostate Specific Antigen antibody [A67-B/E3] (ab2218)
This product has been referenced in:
- Rye P.D. (eds.) et al. Summary Report on the ISOBM TD-3 Workshop. Tum. Biol. 20:1-94 (1999).Read more (PubMed: ) »
See 1 publication for this product
Publishing research using ab2218? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"