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Product Name
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Protein C antibody [BDI540]
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See all Protein C antibodies (12)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [BDI540] to Protein C
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Immunogen
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Full length native protein (purified): Human Protein C derived from human blood.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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ELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Cardiovascular >> Blood >> Coagulation >> Regulatory
Cardiovascular >> Blood >> Fibrinolysis / Thrombolysis
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Relevance
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Protein C is a vitamin K dependent serine protease zymogen. Purified human activated protein C selectively destroys factors Va and VIII:C in human plasma and thus has an important anticoagulant role. Protein C deficiency has been associated with inherited thrombophilia. In its primary structure, protein C is similar to the prothrombin group of blood coagulation factors. It most closely resembles factor X.
Protein C is synthesized as a single chain; this precursor molecule is cleaved into a light chain and a heavy chain held together by a disulfide bond. The enzyme is then activated by thrombin, which cleaves a tetradecapeptide from the amino end of the heavy chain.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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BDI540
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Isotype
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IgG2b
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
Constituents: Lyophilized from: 10mM PBS, pH 7.2
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Purification notes
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Purified from ascites.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Protein C antibody [BDI540] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Protein C
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Protein C antibody [BDI540] - more information
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