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Product Name
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Protein C antibody
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See all Protein C antibodies (12)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Protein C
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Immunogen
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Full length native protein purified from human plasma
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Reacts with
(species key)
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Hu
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Tested applications
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EIA, RIA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
EIA: Use at an assay dependent dilution.
RIA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 52 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Cardiovascular >> Blood >> Coagulation >> Regulatory
Cardiovascular >> Blood >> Fibrinolysis / Thrombolysis
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Relevance
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Protein C is a vitamin K dependent serine protease zymogen. Purified human activated protein C selectively destroys factors Va and VIII:C in human plasma and thus has an important anticoagulant role. Protein C deficiency has been associated with inherited thrombophilia. In its primary structure, protein C is similar to the prothrombin group of blood coagulation factors. It most closely resembles factor X.
Protein C is synthesized as a single chain; this precursor molecule is cleaved into a light chain and a heavy chain held together by a disulfide bond. The enzyme is then activated by thrombin, which cleaves a tetradecapeptide from the amino end of the heavy chain.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 50% Glycerol, PBS, pH 7.5 Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Thimerosal MSDS
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Form
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Liquid
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Concentration
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Batch dependent within range: 1.10 - 1.10 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Protein C antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Protein C
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Protein C antibody - more information
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Customer reviews (feedback) regarding Protein C antibody |
Customer FAQs regarding Protein C antibody |
Protocols for Protein C antibody |
Price and availability of products related to Protein C antibody |
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Protein C antibody - related products:
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Contact Abcam with a Technical Enquiry about Protein C antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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