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Products:Signal Transduction >> Protein Phosphorylation >> Ser / Thr Phosphatases
Overview
Product name
Anti-Protein phosphatase 1 inhibitor subunit 2 antibody
See all Protein phosphatase 1 inhibitor subunit 2 products (6) ...
Description
Mouse monoclonal to Protein phosphatase 1 inhibitor subunit 2
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: MAASTASHRP IKGILKNKTS TTSSMVASAE QPRGNVDEEL SKKSQKWDEM NILATYHPAD KDYGLMKIDE PSTPYHSMMG DDEDACSDTE ATEAMAPDIL , corresponding to amino acids 1-101 of Human Protein phosphatase 1 inhibitor subunit 2
MAASTASHRP IKGILKNKTS TTSSMVASAE QPRGNVDEEL SKKSQKWDEM NILATYHPAD KDYGLMKIDE PSTPYHSMMG DDEDACSDTE ATEAMAPDIL
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Phosphatases
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Western blot - Protein phosphatase 1 inhibitor subunit 2 antibody (ab58149)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab58149 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Inhibitor of protein-phosphatase 1.
Sequence similarities
Belongs to the protein phosphatase inhibitor 2 family.
Post-translational
modifications
Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.
Target information above from: UniProt accessionP41236
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- IPP 2 antibody
- IPP-2 antibody
- IPP2 antibody
see all
Database links
- Entrez Gene: 5504 Human
- Omim: 601792 Human
- SwissProt: P41236 Human
- Unigene: 535731 Human
Anti-Protein phosphatase 1 inhibitor subunit 2 antibody images:
Western blot - Protein phosphatase 1 inhibitor subunit 2 antibody (ab58149)
Western blot against tagged recombinant protein immunogen using ab58149 Protein phosphatase 1 inhibitor subunit 2 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa
References for Anti-Protein phosphatase 1 inhibitor subunit 2 antibody (ab58149)
ab58149 has not yet been referenced specifically in any publications.
Publishing research using ab58149? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"