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Products:Neuroscience >> Neurotransmitter >> Amino Acids >> Other
Overview
Product name
Anti-QPCT antibody
See all QPCT products (2) ...
Description
Mouse monoclonal to QPCT
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: PNSARWFERL QAIEHELHEL GLLKDHSLEG RYFQNYSYGG VIQDDHIPFL RRGVPVLHLI PSPFPEVWHT MDDNEENLDE STIDNLNKIL QVFVLEYL, corresponding to amino acids 262-360 of Human QPCT
PNSARWFERL QAIEHELHEL GLLKDHSLEG RYFQNYSYGG VIQDDHIPFL RRGVPVLHLI PSPFPEVWHT MDDNEENLDE STIDNLNKIL QVFVLEYL
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Signal Transduction >> Metabolism >> Amino Acids
Neuroscience >> Neurotransmitter >> Amino Acids >> Other
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Western blot - QPCT antibody (ab57038)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab57038 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.
Alternative names
- GCT antibody
- 5730422A13Rik antibody
- EC antibody
see all
Database links
- Entrez Gene: 25797 Human
- Omim: 607065 Human
- SwissProt: Q16769 Human
Anti-QPCT antibody images:
Western blot - QPCT antibody (ab57038)
Western blot against tagged recombinant protein immunogen using ab57038 QPCT antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa
References for Anti-QPCT antibody (ab57038)
ab57038 has not yet been referenced specifically in any publications.
Publishing research using ab57038? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"