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Anti-QPCT antibody (ab85183)

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Overview

Product name

Anti-QPCT antibody
See all QPCT products (2) ...

Description

Rabbit polyclonal to QPCT

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Sheep, Cow

Immunogen

Synthetic peptide within residues: SRHLAAKMAS TPHPPGARGT SQLHGMDLLV LLDLIGAPNP TFPNFFPNSA , corresponding to internal sequence amino acids 216-265 of Human QPCT (NP_036545)

Positive control

Human fetal muscle lysate.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

ab85183 is purified by a peptide affinity chromatography method.

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Metabolism >> Amino Acids
Neuroscience >> Neurotransmitter >> Amino Acids >> Other

  • Western blot - QPCT antibody (ab85183)Western blot - QPCT antibody (ab85183) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab85183 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 1 µg/mlDetects a band of approximately 38 kDa (predicted molecular weight: 38 kDa).

Target

Relevance

Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.

Alternative names

  • GCT antibody
  • 5730422A13Rik antibody
  • EC antibody
  • Glutaminyl cyclase antibody
  • Glutaminyl peptide cyclotransferase antibody
  • Glutaminyl tRNA cyclotransferase antibody
  • Glutamyl cyclase antibody
  • QC antibody
see all

Database links

Anti-QPCT antibody images:

  Western blot - QPCT antibody (ab85183)

Western blot - QPCT antibody (ab85183)

Anti-QPCT antibody (ab85183) at 1 µg/ml + Human fetal muscle lysate at 10 µg

Secondary
anti-Rabbit IgG HRP at 1/50000 dilution

Predicted band size : 38 kDa
Observed band size : 38 kDa

References for Anti-QPCT antibody (ab85183)

ab85183 has not yet been referenced specifically in any publications.

Publishing research using ab85183? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"