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Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Huntington's disease
Overview
Product name
Anti-QPRT antibody
See all QPRT products (4) ...
Description
Chicken polyclonal to QPRT
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide, corresponding to Internal sequence amino acids 123-237 of Human QPRT
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgY
Research areas
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Signal Transduction >> Metabolism >> Amino Acids
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Neuroscience >> Neurology process >> Neurodegenerative disease >> Huntington's disease
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Western blot - QPRT antibody (ab37515)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab37515 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: 1/2000. Detects a band of approximately 65 kDa (predicted molecular weight: 31 kDa). A fusion protein was used in this blot, hence the difference in M.Wt as compared to native protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Involved in the catabolism of quinolinic acid (QA).
Pathway
Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.
Sequence similarities
Belongs to the nadC/modD family.
Target information above from: UniProt accessionQ15274
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Quinolinate phosphoribosyltransferase antibody
- NADC_HUMAN antibody
- Nicotinate nucleotide pyrophosphorylase (carboxylating) antibody
see all
Database links
- Entrez Gene: 23475 Human
- Omim: 606248 Human
- SwissProt: Q15274 Human
- Unigene: 513484 Human
Anti-QPRT antibody images:
Western blot - QPRT antibody (ab37515)
Anti-QPRT antibody (ab37515) at 1/2000 dilution + E. coli-derived fusion protein at 2.5 µg
Secondary
Goat anti-IgY-HRP at 1/1000 dilution
Predicted band size : 31 kDa
Observed band size : 65 kDa (why is the actual band size different from the predicted?)
Band size larger than expected as a fusion protein was used as positive control.
References for Anti-QPRT antibody (ab37515)
ab37515 has not yet been referenced specifically in any publications.
Publishing research using ab37515? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"