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IHC-P - QPRT antibody (ab57125)
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Western blot - QPRT antibody (ab57125)
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Product Name
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QPRT antibody
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See all QPRT antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to QPRT
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Immunogen
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Recombinant fragment: VEVECSSLQE AVQAAEAGAD LVLLDNFKPE ELHPTATVLK AQFPSVAVEA SGGITLDNLP QFCGPHIDVI SMGMLTQAAP ALDFSLKLFA KEVAPVPKIH , corresponding to amino acids 198-298 of Human QPRT
BLAST 'VEVECSSLQE AVQAAEAGAD LVLLDNFKPE ELHPTATVLK AQFPSVAVEA SGGITLDNLP QFCGPHIDVI SMGMLTQAAP ALDFSLKLFA KEVAPVPKIH ' with  or 
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Reacts with
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Hu
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Tested applications
(see key)
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IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Signal Transduction >> Metabolism >> Amino Acids
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Neuroscience >> Neurology process >> Neurodegenerative disease >> Huntington's disease
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Relevance
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QPRT is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease and Huntington's disease.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this QPRT antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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QPRT antibody images:
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 IHC-P - QPRT antibody (ab57125)
QPRT antibody (ab57125) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.
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Western blot - QPRT antibody (ab57125)
Predicted band size : 31 kDa
QPRT antibody (ab57125) at 1ug/lane + HepG2 cell lysate at 25ug/lane.
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Search PubMed (MEDLINE) for references to QPRT
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QPRT antibody - more information
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Customer reviews (feedback) regarding QPRT antibody |
Customer FAQs regarding QPRT antibody |
Protocols for QPRT antibody |
Price and availability of products related to QPRT antibody |
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QPRT antibody - other tools:
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Contact Abcam with a Technical Enquiry about QPRT antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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